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Ctni (Phospho S22/S23) Polyclonal Antibody
Background Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardi
Description
Basic Info
| Model NO. | BS64505 |
| Specification | 100ug/1mg |
| Trademark | Bioworld |
| Origin | China |
| Production Capacity | 3000 Vials |
Product Description
| Catalog No. | BS64505 |
|---|---|
| Product Name | cTnI (Phospho-S22/S23) polyclonal antibody |
| Applications | WB IHC |
| Alternative Name | Troponin I, cardiac muscle; Cardiac troponin I; TNNI3; TNNC1 |
| Swiss-Prot | P19429 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Application_all | WB: 1:500~1:1000 IHC: 1:50~1:200 |
| Product | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
| Purification&Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
| Storage&Stability | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Specificity | cTnI (Phospho-S22/S23) polyclonal antibody detects endogenous levels of cTnI protein only when phosphorylated at Ser22/Ser23. |
| BiowMW | ~ 28 kDa |
| Note | For research use only, not for use in diagnostic procedure. |
| Immunogen | Synthetic phosphopeptide derived from human cTnI around the phosphorylation site of Serine 22/Serine 23. |
Western blot (WB) analysis of cTnI (Phospho-S22/S23) polyclonal antibody at 1:500 dilution LaneA:The Heart tissue lysate of Mouse LaneB:The Kidney tissue lysate of Mouse LaneC:The Heart tissue lysate of Rat LaneD:The Kidney tissue lysate of Rat
Background
Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.
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